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Re: Multiple Intolerances to Antidepressants

Posted by Racer on July 21, 2004, at 14:02:14

In reply to Multiple Intolerances to Antidepressants, posted by Josh37 on July 20, 2004, at 21:01:11

Ugh, this is a problem I can certainly relate to, although my problems with most of the anti-depressants I've tried have been a little more limited: worst from an objective standpoint is hypotension, worst subjectively is weight gain, with anorgasmia running a close second (although this would really only matter if I had a sex life), and a few other bothersome problems running in a pack somewhere behind those.

As for 'fixing' the problem of intolerance, I'm not sure what the answer is. It's a subject I struggle with a lot, and the closest I've come to an answer for myself is that I'm gonna have to put up with a certain amount of discomfort in order to treat the depression. Sounds kinda easy, huh? (NOT) My situation is a little complicated, because I am relying on a very, very broken county system for treatment, so I can't test my theory that adequate support from the doctor in getting through the adjustment phase might allow me to tolerate the adverse effects of the drugs, but that is my theory. I hope that, once I get to play with the Big Boys and see a doctor in more optimal circumstances, I'll be able to address the issue of reassurance and support, and thereby get through the adjustment phase and *finally* get adequate relief from my depression. That might be something to think about for you, too.

A lot of the side effects, by the way, are alleged to fade away once your body adjusts to the new medications. It's possible that the problems you've been having will go away if you can gut them out for a few weeks. (In my case, that hasn't been possible with some drugs, because the adverse effects have been too dangerous in and of themselves: ranging from frequent fainting, to increased suicidal impulsivity, to one experience where I actually threatened my husband! Sometimes gutting it out just ain't in the cards, but if you are able, it might be worth a try.)

If you have a good rapport with your pdoc, you could discuss ways to mitigate some of the adverse effects of the meds, too. Some effects can be lessened, although some just cannot.

Other than those thoughts, not much else I can offer, except to say that augmenting the meds with therapy can also be helpful in getting through some of the adjustment problems.

It might help, though, if you give a full list here of the meds you've tried. There are a lot of very well informed people here, and some of them seem to know more about alternative medications than a lot of doctors. If they know the specifics, they may be able to see something you haven't tried.




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