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Re: Surmontil/trimipramine for sleep, ibs Larry Hoover

Posted by yeltom on July 20, 2004, at 22:43:58

In reply to Re: Surmontil/trimipramine for sleep, ibs yeltom, posted by Larry Hoover on July 20, 2004, at 19:42:55

I couldn't take zoloft for that reason. Actually, when used for IBS, tricyclics are generally effective at very low doses. Amitriptyline has been successful at doses as low as 2.5 mg (not a misprint), so 25 mg might be plenty. You might be able to give up the Dictel or use less of it. What is Dictel?

> > Thanks for respoding. I actually had already read that abstract. How much are you taking?
> 25 mg, one hour before sleep.
> > Are you taking it for sleep, ibs, to augment the zoloft?
> The intent was to help with insomnia, which Zoloft made worse. I didn't know about the IBS link until today, and though I have IBS, I don't think my dose is large enough to affect that. Zoloft, initially, and at each dose increase, provoked extraordinary diarrhea that lasted days. My IBS med, Dicetel, fixed that problem up.
> > How is it working?
> It helps initiation of sleep. I also use 30 mg temazepam. The effect of the trimipramine seems to be diminishing over time. I expect I'll have to increase the dose. For primary insomnia, the dose is 100 mg, so I've got a ways to go, yet.
> > How bad are the side effects?
> Bit of dry mouth, but that passed after a week or so. Also, tended to sleep without moving for extended periods, and waking crampy. That passed, too.
> > Let me know, will you. Thanks
> You're welcome.




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