Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Histamine H1 - Drugs to increase activity? SLS

Posted by Larry Hoover on July 19, 2004, at 9:59:05

In reply to Histamine H1 - Drugs to increase activity?, posted by SLS on July 19, 2004, at 7:24:39

> Hi.
>
> I am interested in how histaminergic pathways might be involved in depression and bipolar disorder. Are there any drugs that act as H1 receptor agonists or otherwise promote histaminergic neurotransmission? Do such things exist?
>
>
> - Scott

Yes, H1 histamine agonists are known. One of the central roles of histamine in the brain is as a participant in the diurnal wake/sleep cycle. For an H1 agonist drug to be useful, IMHO, its uptake and clearance time must also be in accord with the oscillations in e.g. melatonin, HGH, cortisol release which accompany movement through this cycle. Histamine does other things, too. Just what aspect of histamine function would you be trying to tweek?

Lar

 

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Larry Hoover thread:367673
URL: http://www.dr-bob.org/babble/20040719/msgs/367708.html