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tricyclic and benzodiazepine interaction

Posted by Squiggles on July 18, 2004, at 11:56:26

In reply to Re: tricyclic and benzodiazepine interaction » Squiggles, posted by Sad Panda on July 18, 2004, at 11:37:33

> > Hello again,
> >
> > Has anyone experienced the following results
> > from mixing clonazepam with imipramine?
> >
> > - rapid weight loss
> > - lassitude, apathy, lack of libido, anorexia
> > - fatigue
> > - feeling and being cold even in very hot weather
> > - diarrhea
> > - and last but not least, blessed ability to sleep
> > which was the reason for adding clonazepam to anxiety provoking imipramine;
> >
> > If these symptoms are normal, then it's worth
> > the combo. But I am a bit worried if these
> > are symptoms of something more serious - hopefully
> > a CBT will tell.
> >
> > Also, is clonazepam combined with imipramine, more likely to induce these symptoms, than say another benzo?
> >
> > Thanks for reading, and looking forward to
> > any feedback from your experiences.
> >
> > Squiggles
> >
>
>
> Hi Squiggles,
>
> They are unusual symptoms, how long have you been taking these two? I would get a liver test. Apathy, lack of libido & fatigue could be side effects of Imipramine, but rapid weight loss certainly isn't. With Imipramine & a benzo combined, you are more likely to be constipated, gain weight, be hot & sweaty. If anxiety is your main problem, you would probably be better off with Amitriptyline or Clomipramine instead.
>
> Cheers,
> Panda.
>
>

Thanks Panda,

I look forward to the results of a
complete blood test - it is useful
to know that these symptoms are not
necessarily connected to this drug
combo. And, a question for alternatives
may be due.

Thanks very much - a couple of weeks from
now the appointment should bring results.
Could be gastro-related after a gall bladder
removal.

Thanks.

Squiggles
>


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poster:Squiggles thread:367093
URL: http://www.dr-bob.org/babble/20040714/msgs/367372.html