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Re: Anyone have a *BAD* experience with Parnate?

Posted by cybercafe on June 9, 2004, at 1:31:58

In reply to Re: Anyone have a *BAD* experience with Parnate?, posted by harryp on June 8, 2004, at 20:27:44

> Worst things I have heard about Parnate:
>
> 1. Some people experience tachycardia (rapid pulse). Usually this can be avoided by breaking up dosages and avoiding caffine until you know how you will respond to it. I have heard of at least one person on this board who had to stop the drug because of this effect--no harm done.
>
> 2. Orthostatic hypotension, where a person gets a sudden loss in bp when standing up. It ususally goes away--breaking up dosages helps, as does getting up slowly.
>
> 3. Physical fatigue--this was noticeable when I went on the drug and increased the dosages. This SE went away completely for me, though.
>
> 4. Sensitivity to cold--very weird effect. I was constantly wearing sweaters and piling blankets on my bed. I think this has gone away, but since it's summer I'm not sure!
>
> 5. Insomnia--this can be relieved by Trazodone (which IS safe at low dosages w/Parnate according to the best MAOI literature). I use half a 50mg pill at night and sleep very well.
>
> 6. Most users love the stimulant effect of this AD--some find it overstimulating though.
>
> 7. I have heard of people who didn't like the strong emotions they felt on Parnate (unlike every other AD I've taken--Parnate DOES NOT blunt emotions; you can feel wonderful or miserable (in a normal way).
>
> In short--watch the diet and read up on EVERY drug you think of taking with it, and you will probably have no problems. I'm amazed that this much-maligned MAOI seems (in general) to have the best SE profile of ANY AD, in addition to being one of the most effective.

combining abilify with parnate seems to give me a little orthostatic hypotension when i do martial arts (otherwise unnoticeable) and worsened my acne (already had high testosterone/bad acne though)


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