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Re: Amphetamines:

Posted by Keith Talent on June 7, 2004, at 14:38:31

In reply to Re: Amphetamines: sensitisation or tolerance or both? » Keith Talent, posted by jodeye on June 6, 2004, at 22:36:45

> Do you have the links to these abstracts? I do not know how to search PubMed for studies by a particular institute. I am very interested in reading them.

I don't know how to give you direct links, but here is how I found the material:

Go to:

http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?CMD=Display&DB=pubmed

Basically, I used the MeSH Database search under PubMed Services (on the left column). If you don't know how to use this, just cut and paste from below:

Search PubMed for ("Dextroamphetamine/administration and dosage"[MeSH] OR "Dextroamphetamine/pharmacology"[MeSH] OR "Dextroamphetamine/therapeutic use"[MeSH]) AND "Drug Tolerance"[MeSH]

Limits: only items with abstracts, Human

Sort by: Pub Date
Show: 50

Display Abstract

-> should give 22 articles

Use your browser to find new york state psychiatric institute -> article 2 (PMID: 11441429)

There are plenty of other interesting articles as well, and you can play around with the Limits settings to see animal studies or limit it to only randomised controlled trials, for example.

> I have read preclinical data stating that memantine can prevent stimulant sensitization. I have also read AndrewB's testimonials of memantine or acamprosate preventing stimulant tolerance. It almost seems as if AndrewB's prevention of stimulant tolerance could have also been a prevention of stimulant sensititization, allowing him to take higher doses. Oh well... I'm done rambling.

I'd heard memantine talked about to preventing and/or reversing stimulant tolerance, but not acamprosate. The latter is used to reduce ethanol cravings, right?

Happy reading Jay,

Keith


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