Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: thanks for the info, and another ? zeugma

Posted by King Vultan on May 26, 2004, at 12:42:39

In reply to thanks for the info, and another ? King Vultan, posted by zeugma on May 25, 2004, at 18:46:57

> By the way, do you think clomipramine + stimulant comes as close to an MAOI as is possible without actually taking one? My thought is that it might COMBINE the attributes of Parnate and Nardil. (In this comparison I would also include the GABAergic effects of the clonazepam I also take.)

Well, clomipramine is basically an SSRI with a powerful affinity for serotonin and a relatively low selectivity ratio for 5HT over NE reuptake, meaning that it is also relatively strong as far as increasing norepinephrine transmission. In that respect, I suppose if you added a stimulant, it might come closer to an MAOI than most of the conventional SSRIs, but the same might be said of adding a stimulant to either imipramine or amitriptyline. Both of these blockade NE and 5HT reuptake at roughly the same order of magnitude. You could also make a case for adding a stimulant to Effexor to attempt to simulate an MAOI.





Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:King Vultan thread:348690