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Re: lamictal and best dosage » scatterbrained

Posted by Tony P on May 25, 2004, at 11:32:39

In reply to lamictal and best dosage, posted by scatterbrained on May 24, 2004, at 14:50:52

> I'm on 300 of lamictal and one day it mildly works and the next day I'm back to my ahedonic, psuedo dementia depression. My P-doc wants to up the dose but I'm concerned that this drug might just be making the cognitive stuff worse and that along with the anhedonia is the worst aspect of my depression.I guess there's only one way to find out although it's hard to trust this doctor because he's so rushed in his approach.I just want to know what the typical dose of lamictal is for depression. He says that 300 is still a pretty low dose but it's hard to trust him.

Standard dose according to manufacturer is 200 mg/day - most people don't get much useful effect below 100. The manufacturer said in their original study there was no benefit going above 200, but everybody's different and my pdoc says he has gone as high as 600 with one patient. I am at 300 mg a day like you, but I am also taking 3-4 mg/day clonazepam - as Viridis said, this can be a good combination, especially if you're like me with mixed anxiety/depression and cylothymia/BP 2 or 3. I am not doing perfectly, but life is better than it was.

I do have some short-term memory and alertness problems, but as my pdoc pointed out, these are also typical symptoms of anxiety and depression! I would like to be on less of everything, or maybe less Lamictal and Clonazepam and a _tiny_ amount of another AD such as Wellbutrin or Effexor, but right now the word from both my pdoc and MD is - if it works, don't fix it.

Whatever you and your pdoc decide, go slowly and gently - Hamba Gashley (my only piece of Zulu).

Tony P


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