Psycho-Babble Medication | about biological treatments | Framed
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Re: Thanks, and... (esp Emme) LastDyingWish

Posted by Emme on May 25, 2004, at 10:36:43

In reply to Re: Thanks, and... (esp Emme), posted by LastDyingWish on May 24, 2004, at 22:00:38

> Emme, would you be so kind to share your experience with selegiline. Iam going to start it this week and need some advice on how much of a dose without overstimulation. anything would help

I haven't taken more than 10 mg and I've taken as little as 2.5 mg. More than 10 mg would be too stimulating. On really bad days when I couldn't move off the couch, it kicked in within a couple of hours. When it kicks in in such a short amount of time, I suspect it's just the result of it metabolizing to amphetamine. Which is fine as long as it get the job done.

It's been helpful no doubt. Some of my best days in the last year have been while on Selegiline. But I've had a tough time figuring out how to take it effectively. By that I mean that at times it's good and at other times it's too stimulating, though not as bad as other stims I've tried. And it seemed like after a little while my moods and energy levels were up and down on it. I don't know if that means it was starting to trigger some mood cycling as an MAOI, or if it was some sort of amphetamine poop out that reversed a bit when I lowered the dose. My pdoc's idea was to "spot treat" depression with it. And it's not a bad idea.

I went through weeks of horrid agitation this winter - I stopped taking it when the agitation set in. After things simmered down, I haven't gone back to it because I wanted to pare down my meds and we wanted to try memantine. That said, I keep it around, and I'd consider using it again. I think it's worth trying. I was more amenable to trying low-dose selegilne than the other MAOIs because I think I'd have a very difficult time adhering to the diet for various reasons.

Good luck,




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