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Re: selegiline + dopamine increase ?

Posted by Ilene on May 24, 2004, at 9:00:41

In reply to Re: selegiline + dopamine increase ?, posted by btnd on May 24, 2004, at 6:29:37

> L-deprenyl plus L-phenylalanine in the treatment of depression
> Birkmayer, W
> J Neural Transmission. (AUSTRIA), 1984, 59/1 (81-87)
> The antidepressive efficacy of deprenyl (5-10 mg daily) plus L-phenylalanine (205 mg/day) has been evaluated in 155 unipolar depressed patients. Both oral and intravenous administration showed beneficial effects in 90% of outpatients and 80.5% of inpatients. It is concluded that this combined treatment has a potent antidepressive action based on the accumulation of L-phenylethylamine in the brain.

Because this study is 20 years old I thought there would be some follow-up, so I went into Medline and looked. I found very little, except about Parkinsons Disease. Looks like this research went nowhere. I wonder why. Someone with access to an academic library might look in the Science Citation Index/Web of Science.





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