Posted by chemist on May 12, 2004, at 12:03:49
In reply to Calcium homeostasis Mood disorders, posted by Civ on May 11, 2004, at 13:38:50
> Can anyone explain the link between calcium homeostasis and mood disorders in layman's terms?
hi there, one of the proponents of calcium-channel blockers for use in bipolar disorder in Dr. Steven L. Dubovsky, and there is a book entitled ``Concise Guide to Mood Disorders,'' by Dubovsky and Dubovsky, publised by American Psychiatric Publishing, Inc. (Washington, DC; London, England), 2002, that might be of use for this and other questions. i am aware of one positive trial of the use of verapamil in treatment of mania in women (Wisner et al., Biol. Psych. 51:745-752, 2002) and one in which verapamil was not superior to placebo (Janicak et al., Am. J. Psychiatry 155:972-973, 1998). however, i do not follow maintainence of calcium regulation in the context of mood disorders in my research, but what little i know points to it being one of many players involved in what i think can best be described as a disorder that is not completely understood. sorry for the run-around, maybe these references can help, all the best, chemist