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Re: Remeron + Nardil...safety precautions..URGENT!!!! » ace

Posted by Sad Panda on April 30, 2004, at 1:36:35

In reply to Remeron + Nardil...safety precautions..URGENT!!!!, posted by ace on April 30, 2004, at 0:20:53

> Starting this combo tonight....seeing my doc in a minute....apart from cyproheptadine (serotonin syndrome) and nifedipine (hypertensive crises), what would i need in case a problem interaction arises between the two??
>
> This will be my combo...
> Nardil 75mg
> Zyprexa 2.5mg
> Remeron 15mg
>
> Hurry! Cause i gotta see my doc real soon!
>
> Ace
>

Hi Ace,

The current best treatment of SS(serotonin syndrome) is with 5-HT2A antagonists. Chlorpromazine & cyproheptadine are the prefered drugs for treatment of SS as they are potent 5-HT2A blockers, lots of drugs are great 5-HT2A blockers, Remeron is one of them, so while you are taking Remeron you have less chance of SS. This also explains why amitriptyline can be taken with MAOI's even though it is a moderate SRI as it is a good 5-HT2A blocker.

Cheers,
Panda.



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