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Re: Provigil appetite enhancer - OOOOHHHH NNNOOOOO

Posted by TJB on April 21, 2004, at 7:23:53

In reply to Re: Provigil appetite enhancer - OOOOHHHH NNNOOOOO, posted by psychosage on April 20, 2004, at 19:06:34

It was on for Patent 6,455,588. It had to do with compositions including modafinil for appetite stimulation. Without repeating the whole abstract it discussed how modafinil is able to stimulate orexin activity in the lateral hypothalamus. Supposedly the lateral hypothalamus is implicated in eating behavior.
I've heard of a few people saying they gained weight when starting Provigil but it seemed like most of those people were Narcoleptics who had been on other stimulants and had switched. I just assumed that the change from a more stimulating drug with greater appetite suppressing effects to Provigil was the reason.
I'm just a little nervous about the weight gain thing since there have been a number of medications that were originally not supposed to cause weight gain. Then, as we all know, these same meds ended up causing exactly the opposite.
I'd love to know what others have experienced.




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