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Re: Nardil from Australia = 1950's version.KV

Posted by Spotcheck on April 10, 2004, at 20:25:24

In reply to Re: Nardil from Australia = 1950's version., posted by King Vultan on April 9, 2004, at 19:55:14

Hello Todd,

As for Pfizer's reason for changing Nardil formulation, that truth is most probably disputable by us. On one hand, I have some old Nardil dispensed to me in the calendar year 2000 which is potent to this day. Hence, using this information, it's rather difficult for me to believe the change was necessary. You have never used this formulation before, and so you cannot know that it is indisputable a better formulation than the one that exists today and what you are taking right now. There is nobody would not go back to the old Nardil ASAP -- if they could -- that is at least among the 50 people or so that I have talked to in the last year. You would too!

On the other hand, Pfizer's Subsidiary Parke-Davis, apparently had some potency problems with Nardil and had to recall several lots. Some people were dispensed a medication which did not work, thus causing their symptoms to reappear. I honestly do not know that the problem here was, but if an excipient suddenly was no longer available, it could indeed force a change to a different formula. Since you know more about this than I do, I will leave up to your imagination as to what actually caused Pfizer to change, but her
statement is generally both shelf-life and dissolution rate.

Here's is what I would very much like to address with you, however, especially since you brought it up:

"In any case, if a person happens to be one of the individuals who is sensitive to the formulation change but can restore the original effects just by taking an extra pill or two, that doesn't sound that horrible."

Agreed, but what happens to the individuals who do not respond well or at all the new formulation? Would you care to hazard a guess as to what happens to them? That is what I honestly want to know. Excuse me very much if this appears belligerent. I just happen to know several people who are in exactly this position. I could sure use any ideas that might assist them.





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