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Re: Antihistamines/Periactin for sexual side effects? » Janelle

Posted by Sad Panda on April 10, 2004, at 15:05:15

In reply to Antihistamines/Periactin for sexual side effects?, posted by Janelle on April 10, 2004, at 13:49:34

> I told my pdoc about sexual side effects I've been experiencing on Celexa (SSRI) and she suggested that I could take an antihistamine called Periactin to help with this. A previous pdoc had also recommended an antihistamine (a different one, I can't remember the name).
>
> I already feel like a walking drugstore, I really do not want to add a med just to offset another, although I would not be taking the Periactin on a regular basis.
>
> I suppose I could explore switching to Wellbutrin as my AD, but SSRI's help me and I hear negative things about Wellbutrin so I'm scared to rock the boat.
>
> Has anyone tried the antihistamine approach to offset sexual side effects from an SSRI? If so, did it help?
>
> Thanks.
>

Hi Janelle,

Here is some opinions on Periactin from older posts here at Dr.Bobs: http://www.google.com/search?q=+site:www.dr-bob.org+Periactin+anorgasmia&num=100&hl=en&lr=&ie=UTF-8&oe=UTF-8&newwindow=1&filter=0

Periactin probably works by being antiserotonin, it's anithistamine effect actually has little to do with temporarily fixing SSRI induced anorgasmia. I haven't tried it myself, but it looks like it does work & it certainly looks harmless enough.

I take Remeron primarily for sleep, but it also fixes my anorgasmia problem caused by Effexor. Remeron is the most potent antihistamine type drug on the market. It also antagonises the serotonin receptors 2A, 2C & 3. My guess is it's 2A & 2C that relieve anorgasmia.

Cheers,
Panda.


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