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ssri question

Posted by dondon on March 8, 2004, at 22:42:20

Before ssri's came out, why didn't the drug companies
design their drugs to inhibit serotonin reuptake
along with blocking the 5-ht2 and 5-ht3 receptors?
They knew that nonselective stimulation of these receptors
caused the unwanted sexual side effects and that
stimulation of the 5-ht1 receptor was the mechanism
behind these drugs. I know that Prozac blocks
5-ht2c receptor. Also, does a reuptake inhibitor stimulate
the neurotransmitters receptors? Bupropion is a da reuptake
inhibitor(also stimulates d1,d2,d3 receptors). Noradrenaline
reuptake inhibitors would also stimulate central
noradrenergic receptors.


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poster:dondon thread:322277
URL: http://www.dr-bob.org/babble/20040308/msgs/322277.html