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Re: Tricyclic antidepressants queries

Posted by Chairman_MAO on February 13, 2004, at 7:29:53

In reply to Re: Tricyclic antidepressants queries, posted by Keith Talent on February 12, 2004, at 23:39:37

Does a1 blocking cause impotence? Vasodialation is key for erection, and I read one anecdotal report on here where Flomax, a selective a1 blocker, was used to correct urinary hesitancy and impotence on reboxetine.

I think it is important to note that we're really talking about a dose-dependent a1 ANTAGONISTIC action, not an absolute all-or-nothing "block". A good analogy here is that stimulants are still effective in treating ADHD when antipsychotics are used concurrently. Thus, even a1 agonists such as modafinil probably work along with TCAs; one might simply have to use higher doses.


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URL: http://www.dr-bob.org/babble/20040210/msgs/312734.html