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Seroquel/Effexor balancing act

Posted by Lyrical13 on February 12, 2004, at 6:26:26

In reply to Re: Seroquel, posted by Doctor Feel Good on February 11, 2004, at 1:25:31

Seroquel has been a miracle for me too. Back in Sept when i had maxed out my Effexor and was still having a terrible time with depression/ anxiety...couldn't even function at work..I was falling apart. Adding Seroquel turned things around in a matter of days. I got through the fall much better than I ever remember. I was actually happy about returning to work after Christmas break..usually I feel a little depressed.

Here's the question for me. Last year in the spring (approx March through June really) I was on 150mg Effexor. I was more hypomanic than I ever remember being. First time I ever felt euphoric. Lots of spending sprees and decreased need for sleep. At that time we still thought I had depression w/ GAD. Now realize it's actually BP2. Seroquel was first being used to augment Effexor for depression/GAD. Now we are increasing the dosage to use it as a mood stabilizer. Currenlty on 225mg Effexor, 75mg Seroquel. (I am very sensitive to meds and often require only pediatric dosage) Working our way up to 100-200 mg of Seroquel and then plan to decrease teh Effexor to 150 or possibly 75mg.

I have been absolutely crawling out of my skin. Hyper, can't sit still, can't shut up. Worked out yesterday afternoon and did some yoga..that helped some. But still very jumpy/antsy...flying high. I have read that Effexor can cause hypomania so I'm wondering if it is exacerbating my hypomania that's part of BP2. If Seroquel is giving the Effexor a boost is that even adding to that effect rather than stabilizing me? I left a msg for pdoc asking about decreasing Effexor now to 150mg as we continue to increase the Seroquel. Haven't heard back yet. Does that make sense to anyone else besides me? Has anyone had similar experiences or using Effexor with Seroquel to treat BP2? Thanks in advance for any feedback.





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