Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: NO! you need to taper and washout!

Posted by djmmm on January 29, 2004, at 17:38:21

In reply to NO! you need to taper and washout!, posted by missliz on January 29, 2004, at 2:17:03

> A lot of people need more than 60 mg- which blows my mind, because I was booming on 30 mg. Parnate doesn't "poop out". The stuff is basicly methamphetamine, with a few other choice metabolites.

--that just isn't true, you are confusing the MAO-B inhibitor Deprenyl, which has amphetamine metabolites. Parnate is structurally similar to amphetamine, it is not derived from or metabolized into any form of amphetamine. It is simply similar in chemical structure...example: Effexor is a phenylalanine, as is the street drug Ecstacy...similar..but VERY different.

It works- you just need enough of it. There's a bonafide problem of undermedication of deppressive illness in this country- it's 'cause the PDR is written by company lawyers. What people on this board call poop out is usually just time to titrate the dose up again but the bottom of the class people who get shunted into psych won't do it. May I suggest a second opinion? Or a new doctor?
> If he switches, he needs to taper the dose down for a few weeks and then do the two weeks. The chemistry is too tedious to write out- but there is any ruler of the MAOI it's me. The washout is very important. Gruesome, but better than stroking out.

-- A wash out of 2 weeks is not necessary form Parnate to Nardil, a short washout is recomended when switching from Nardil to Parnate, but only because Nardil is an irreversible MAOI, and accumulates in the liver.

> Parnate is manufactured from amphetamine; Nardil is made from antibiotics, which were the original MAOIs.

-- Wrong, I'm sorry, Nardil is a hydrazine derivative, it has nothing to do with antibiotics, hydrazine is actually rocket fuel. MAOI activity was originally discovered via the use of anti-malaria meds.

It's gentler, causes weight gain in some people, I LOVED it. So good to be normal! Drank gallons of coffee on it, but I was in grad school a lot of that time. The lifestyle.
> I think a higher dose deserves a chance- or, here's a cool trick, you can goose an MAOI with lithium and see if that gets it moving. I reccomend Lithobid over the generic, a small dose should do it. Do not under any circumstanses take a diuretic with this combo- Parnate and thiazide diuretics are potentially lethal. Bet nobody knew that, did you? ;D Neither does your shrink- it isn't in the PDR, but it's in the formularies of every other nation in the first world.

--it does state in the PDR not to combine thiazides with MAOIs

> If the shrink doesn't know any of this, he's in over his head and you need a real psychopharmacologist. MAOIs are the big leagues of treatment, and depression that severe needs a doc who knows what he's doing.
> Is he on anything else?
> This is all meant to be tried under the supervision of a pdoc who knows what they're doing, of course, but there are more things to try with the Parnate. Good luck.
>
> Lizzy

--With all due respect, Where on earth did you hear all of this false info on MAOIs??


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:djmmm thread:305978
URL: http://www.dr-bob.org/babble/20040127/msgs/307007.html