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Re: High doses of Dexedrine

Posted by MaTurtle on January 4, 2004, at 18:56:27

In reply to Re: High doses of Dexedrine, posted by sean7 on October 24, 2003, at 1:20:42

taken from -

--- OVERDOSE ---
Individual patient response to amphetamines varies widely. While toxic symptoms occasonally occur as an idiosyncrasy at doses as low as 2 mg; they are rare with doses of less than 15 mg; 30 mg can produce severe reactions yet doses of 400 to 500 mg are not necessarily fatal.

In rats, the oral LD50 of dextroamphetamine sulfate is 96.8 mg/kg.

Manifestations of acute overdosage with amphetamines include restlessness, tremor, hyperreflexia, rhabdomyolysis, rapid respiration hyperpyrexia, confusion, assaultiveness, hallucinations, panic states. Fatigue and depression usually follow the central stimulation.

Cardiovascular effects include arrhythmias hypertension or hypotension and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea and abdominal cramps. Fatal poisoning is usually preceded by convulsions and coma.


I'm pretty sure most people survive and recover from amphetamine overdoses, unless they are intolerant or hypersensitive. If your scared that you have overdosed just look for the symptoms of an overdosage. If you start to freak out, don't worry your probobly just paranoid from the amphetamines. I would only worry if you have heart or cardiovascular problems like hypertension or arrythmia. I would only worry about overdose in healty people if a tolerant person has taken 300+mg or an intolerant person taking 150+mg. but if your hypersensitive you could od on a smaller dose. Some meth addicts shoot 4-8 grams of methamphetamine into there viens and still live and eventually recover. D-amphetamine(dexedrine) is not as strong or long acting as methamphetamine(I'm not sure if it's actually stronger), meth has less cardiovascualr effects than adderall though, but I'm not sure about d-amphetamine(dexedrine)'s periphrial nervous system effects. A while back ago I took 200mg adderall xr in one day, and had a little paranoia/insomnia, but it was nothing like when I took two hits of meth from a pipe and was up for 3 days scared shitless. I OD from meth that one time and I was fine after my stomach stopped hurting and I ate and got some sleep, but it took 3 days. I'd say you know you have overdosed if you start to hallucinate and get visual disturbances, and you may think your going to die or something, you probobly won't you just think your going to die becasue your paranoid or maybe having a panic attack. Ushually when I start noticing my breathing and think I have to concentrate to take every breah or else I'll stop breathing, thats when I know I'm having a panic attack. That kind of stuff has happened to me on psychdelics too, the breathing thing. I don't do drugs anymore, but sometimes I do occassionally have to take a xanax for panic attack, but I only take 15mg dexedrine a day. When I abused it I think I only took like 40-80mg a day, so I can not say from personal experience what it's like to od on d-amph(dexedrine), although I'm sure it would be similar to the time I od on meth.

All in all becasue people react differently to chemicals, if your worried about some oding on amphetamines, check thier heart rate, if it's not dangerously high then they are just paranoid. However I'd be very worried if somone took a massive dosage and had a hard time walked or passed out, but you would have to take alot to make you pass out or lose motor control. Just be careful and monitor your heart rate, and hope to hell they don't start convulsing and going into a coma. I'd cry if I saw somone convulse and die from taking too much amphetamines, addiction makes me sad.




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