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Re: Can some one answer this question please?

Posted by Psychopoppy on December 8, 2003, at 17:31:28

In reply to Can some one answer this question please? , posted by crazychickuk on December 8, 2003, at 16:29:59

Effexor blocks the reuptake of serotonin, norepinephrine and dopamine (in decreasing order of affinity and potency) by their respective receptors on nerve cells and basically lets those neurotransmitters stick around longer and do their job (they each have their jobs in maintaining optimal body and mind functioning).

there is a drug out there which does the opposite of effexor and other SSRIs. Its a serotonin reuptake-enhancer (name= tianeptine). Apparently, this drug has been evaluated in clinical trials and has been found to brighten mood and enhance emotionality (which is what some find helpful, although I think major depression certainly comes packed with enough emotion...mostly negative and painful, so it might not be the best drug for that).

I find it intriguing that both a serotonin reuptake inhibitor and an enhancer can be anti-depressants. A pharmaceutical-paradox !?!?


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