Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: GABITRIL (tiagabine) new anti-anxiety drug????? 3 Beer Effect

Posted by Snowie on December 7, 2003, at 19:12:43

In reply to GABITRIL (tiagabine) new anti-anxiety drug?????, posted by 3 Beer Effect on December 14, 2001, at 22:42:11

Long thread here. I took Gabitril for a short period of time, maybe a little over a month. My pdoc said it was a new drug but he thought it might become a substitute for Neurontin. I don't remember if it had any side effects, but it didn't do anything for GAD or anxiety for me. Wish it had.


> GABITRIL Filmtab Tablets (tiagabine hcl), Abbott Laboratories, PDR p. 449 is an antiepilepsy drug available in 2, 4, 12, 16, & 20 mg tablets. Antiseizure effect of Gabitril from enhancement of activity of GABA, inhibition of GABA uptake into presynaptic neurons which permits more GABA to be available for receptor binding on the surfaces of post-synaptic cells, & increases amount of GABA available in th extracellular space of the globus pallidus, ventral palladum & sustantia negra. This suggests that tiagabine prevents the propagation of neural impulses that contribute to seizures by a GABA-ergic action.
> This drug sounds like it would make a great anti-anxiety drug, since like the benzodiazepine Klonopin it enhances the effect of GABA and it an anti-convulsant and GABATRIL is not a controlled substance like the Benzodiazpines.
> Also, it appears to be superior to Neurontin since Gabitril acts directly on GABA while Neurontin is structurally related to GABA but it is not converted into GABA, or a GABA agonist, does not interact w/ GABA receptors & it is not an inhibitor of GABA uptake or degredation.
> Does anyone have any experience with GABATRIL and/or can comment about its anti-anxiety/social phobia potential?
> Thanks, 3 Beer Effect




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Snowie thread:86944