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Re: I'm coming off of ssris then, 5 years is enough raquo; ian24 » Robert Fairburn

Posted by ace on October 30, 2003, at 16:10:47

In reply to Re: I'm coming off of ssris then, 5 years is enough raquo; ian24, posted by Robert Fairburn on October 30, 2003, at 3:42:27

> Ace are you trying to scare this guy,

No. No. The last thing I want is to scare him. My comments are based on

1. My research (of clinical material) which has looked at BOTH sides of the argument

2. My personal experience with SSRIs in addition to mant anecdotes I have read.

its true that some people have adverse reactions to SSRI drugs after discontinuation, however most people are able to withdraw from these drugs with out major withdrawl symptoms.

I wouldn't say the 'majority' but I agree a lot have no problems. My main worry is with long-term adverse effects. SSRIs are not lollies- they are potent re-uptake blockers. Movement disorders have been reported, including akathisia, and even TD. Lawsuits have been filed (obviously done from pure greed at times, although). They infact cause a depletion of dopamine which has been hypothesised to lead to parkinsons. When excess 5HT is oxidised it turns into a toxic compound which kills neurons.

However these problems are hypothesised to happen after 10 years or so of continued usage.

To be fair I think some negative comments about SSRIs are way off. I do not believe they cause suicide or violent behaviour. And we must remember that a lot of these studies on the dangers of SSRI therapy have been done on animals- not humans.

But there is enough evidence to be concerned, IMO.

Of course everyone should research and come to their own conclusions.

> Overall Im still not a fan of ssri drugs and I will agree if a MAOI drug works for you try and stick with it
>
> Robert


Thanks,
Ace.


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