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Re: Zeugma - some information, please

Posted by Kacy on October 22, 2003, at 19:23:03

In reply to Re: Zeuma - some information, please Kacy, posted by zeugma on October 22, 2003, at 9:24:48

Thanks for the information. I appreciate it.

How long did it take you to get a response to despramine? Does desipramine work on different norepinephrine sites? Is it a re-uptake inhibitor?

I went up to 225 mg. Effexor without any additional benefits. The side effects of a missed dose were too scary. It causes more sexual numbness too. Never got any NE-type response at all, at least not by measuring NE by Strattera and seeing no resemblance in the two drugs. In combination with Strattera, 75 mg. of Effexor works as well as 150 mg. Effexor without Strattera. That drug is for excessive ruminating and does the job well. I don't know why he wants to trade it for desipramine. I don't want the ruminating to come back. Could NE take care of that? Strattera by itself most certainly did not.

Do you mean to say that Effexor could make desipramine cause cardio problems? Could that be why he wants to trade Effexor off?

Strattera has been too sedating on the 100 mg. dose, so that's one of the problems. It's great in the morning, but it backfires in the afternoon. That problem went away at 80 mg. of Strattera as did some of the benefit. It won't go away at 100, so I'm leery of 120. The sedation does seem to be lessening some after five months, but so does the positive benefit. It doesn't help much with Add/inattentive issues but it does wonders for anxiety.

Splitting doses of Stratttera leaves no effect at all. I don't get anything from 60 mg. in the morning and 40 mg. at noon. It must just not be strong enough. I get zip-nada benefit when taking it in the evening. I wake up a little early but want to go back to bed an hour or two later. Unlike anyone else posting anywhere, I am getting only seven hours of response. It's been hard to convince my psychiatrist that it doesn't work 24 hours. Surprisingly, it's half-life is the same as Effexor's and Effexor does work 24 hours a day.

I absolutely don't need sedation. I'm way too sedate as it is, and none of the things that are supposed to be enervating or energizing give me any physical energizing effect. Some mental effect, though.

Sorry about misspelling your name.




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