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Re: Inderal(Propranolol) - Good for Anxiety??? » djmmm

Posted by Ame Sans Vie on September 9, 2003, at 11:57:42

In reply to Re: Inderal(Propranolol) - Good for Anxiety???, posted by djmmm on September 9, 2003, at 8:33:48

I pretty much just would like to echo what djmmm said, having used propranolol on and off over the past year for SP. Just a couple things I'd like to add.

Propranolol *can* be taken on a regular basis, but there really isn't much point to it (for most people). Its purpose is really just to stifle the physical symtpoms of SP on an as-needed basis.

Some people, however, have extremely troublesome problems with sweating, blushing, etc. For these people the best option may be to take the drug on a regular basis. The most attractive option for these people seems, at first glance, to be the once-daily dosage formulations (i.e. Inderal LA [long-acting]). Unfortunately, the lowest dose in which these capsules are available is 60mg, which is more than enough to cause a truly horrible depression, fatigue, and malaise for many people. I had developed these symptoms at only 40mg/day (10mg four times daily of immediate-release propranolol), and they were just awful. I'd never encountered the horrific symptoms of melancholic depression prior to this, but I strongly feel that's what I was experiencing while under the influence of this drug. Upon discontinuation, my symptoms cleared up 100%.

Your best option, generally speaking, is to try a dose of 10-20mg about 30 minutes in anticipation of an experience wherein the physical symptoms of your social anxiety are most prevalent. Very few doctors will have any qualms about prescribing this drug (or any beta-blocker, for that matter) unless, of course, the drug is contraindicated in your particular case.

One final thing to keep in mind is that propranolol increases the effects of clonazepam, which is, generally speaking, the social anxiety treatment of choice (especially amongst patients). Thus, if you are taking clonazepam, it would be wise to discuss with your prescribing physician whether a dosage reduction may be necessary solely on those occasions that require you to take propranolol comcomitantly.


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