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MAOIs: comment.

Posted by Questionmark on September 7, 2003, at 23:32:57

i just wanna say that it bothers me how Nardil and Parnate (and other MAOIs maybe) are lumped together so often, and discussed like they have the same effects and same properties-- not so much by "patients" or whatever like us but by researchers and writers on the subject and stuff. Parnate and Nardil are exTREMely different drugs. They may both irreversibly inhibit both MAO enzymes, but in addition to Nardil's GABA-elevating properties, they do for some reason produce quite different effects-- maybe it's just Parnate's amphetamine-like qualities that make the difference, i don't know. i'm curious. But i personally find Nardil to be considerably more serotonergic than Parnate-- and i could go into a long shpiel about why i believe this but i won't. Anyway, my point is i think it would be much better if we didn't discuss the pros and cons of MAOIs as a group, but as seperate drugs with significantly different effects. The SSRIs are much more similar to each other, in my opinion, than Parnate and Nardil are to each other.


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poster:Questionmark thread:257958
URL: http://www.dr-bob.org/babble/20030907/msgs/257958.html