Posted by Caleb462 on August 28, 2003, at 15:24:29
In reply to Re: Remeron, posted by matthhhh on August 28, 2003, at 13:57:25
> ocd results from low levels of serotonin.
This is an unsubstantiated, likely false claim - though certainly it has become a widely believed, well.. rumor, is the best way to put it. There is no convincing evidence that OCD results from low levels of serotonin.
>ssris increase serotonin in the brain thus reducing ocd. i have never heard of ssris decreasing serotoin
Yes, but SSRIs increase serotonin in the brain in a matter of hours, whereas it takes up to 12 weeks
for OCD symptoms to be reduced. Get what I'm saying?
SSRI therapy HAS BEEN PROVEN to reduce activity at particular serotonin receptors, namely 5-HT2 and 5-HT3 receptors.
The action of SSRIs increases serotonin activity, yes, but their resulting anti-depressant, anti-anxiety, anti-OCDs effect come from changes in the brain that result from long-term therapy... not the increased serotonin itself.