Posted by Ame Sans Vie on August 25, 2003, at 7:28:05
In reply to Re: Prevention of long-term negative effects?, posted by btnd on August 25, 2003, at 1:23:15
> > For example, long-term use of amphetamines I believe could lead to dopaminergic and noradrenergic inadequacy (correct me if I'm wrong on any of this).
> IMO not quite so. Dopamine system is pretty robust when it comes to rebuilding itself (unlike the serotonin). Unless you use high doses of amphetamine-type stimulants, there is no need to worry about dopamine toxicity or inadequacy over time. Although it wouldn't hurt to use anti-oxidants: alpha lipoic-acid, green tea extract, vit.E - anything except Vit.C which, via unknown mechanism, counteracts amphetamine action.
Just for the record, vitamin C expedites excretion of amphetamines... or hinders their absorption... I forget. :-)
> I wouldn't worry about Dexedrine more than about Adderall/Desoxyn. They are pretty much all amphetamines (desoxyn - methamphetamine) with the same method of action, same effects and side-effects in therapeutic doses.
Just to clarify, I meant I was a bit more concerned about the Dexedrine than the Ultram and benzos, not other amphetamines. I've taken amphetamines on and off for seven years, and I just switched from Desoxyn to Dexedrine a few weeks ago... I don't know why I didn't begin to worry until now. But from the information you gave, it appears that all is well. :-)
poster:Ame Sans Vie