Posted by Zenclearer on August 2, 2003, at 10:13:26
In reply to Re: just more evidence...ADs protect the brain » SLS, posted by jrbecker on August 1, 2003, at 17:32:24
Does anyone have any information (or know anything about) neuroprotective potential of Wellbutrin (vs the ssris)?
Most of what I've read regarding BDNF has been associated with the ssri's and some of the cholinergics.
Also, regarding amphetamines (dexadrine, not meth), does anyone have any information about any relations (positive or negative) with BDNF or other neuroprotective properties? I know about neurodegenerative effects (at high doses).
And I am famililar with potentiated neuro-platisticity under learning conditions (very short-term experiments; see recent piece in Science, about working with elderly and potentiating tactile sensitivity, although learning was not retained after stims discontinued).
Essentially, I am somewhat concerned about long-term use of low-does amphetamines. Instinctively, I have some feeling that rebound phenomena activates some inflammatory cascades, etc, and we know that's not good for the Ms. Brain. So I suppose I am more concerned about protential rebound reactions, and the effect on the brain over time.
poster:Zenclearer
thread:247363
URL: http://www.dr-bob.org/babble/20030802/msgs/247570.html