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Re: Paging Larry: DLPA to supplement my tramadol? Ame Sans Vie

Posted by SLS on July 13, 2003, at 20:12:22

In reply to Paging Larry: DLPA to supplement my tramadol?, posted by Ame Sans Vie on July 13, 2003, at 17:36:01

> I noticed in a thread above that you mentioned DLPA's possibility for preventing opioid tolerance and increasing analgesia. I've been taking tramadol for the past week or so now with miraculous results... I know it's a very unconventional opioid, but do you think supplementing with DLPA may help assure that its effects last? Thanks!


I don't know about dl-phenylalanine, but there is a drug named memantine that is supposed to mitigate opioid tolerance. It is closely related to amantadine, and like amantadine, blocks NMDA receptors and is antiglutamatergic. Memantine is available now in Germany, and will probably be approved in the US soon for Alzheimer's Dementia. Another possibility might be acamprosate (Campral). It is also antiglutamatergic.

Hopefully, you won't need anything else.

How does tramadol affect you? Does it help with depression?


- Scott

 

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