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Re: Strattera and Wellbutrin - what's the difference?

Posted by zeugma on July 9, 2003, at 21:01:13

In reply to Strattera and Wellbutrin - what's the difference?, posted by DiscoPuppy on July 9, 2003, at 15:37:33

> Looking at the actions of Strattera and Wellbutrin, it seems very similar to me. They are both considered to be a SNRI.
>
> So what's the difference?


Strattera is a selective norepinephrine reuptake inhibitor, no doubt about it.

Wellbutrin is... well, I don't think anyone knows what Wellbutrin does anymore. Check out this link

http://www.acnp.org/g5/p/SCH79_1139-164.pdf


for the latest on Wellbutrin's mechanism of action, basically unknown at this point.


Speaking anecdotally, the norepinephrine reuptake inhibors Strattera and nortriptyline have been of great benefit to me, while I didn't last three days on Wellbutrin. I think it's safe to say at this point that it's anything BUT a norepinephrine reuptake inhibitor, and hence has little in common with Strattera.


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