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Re: Selenium » blueheeler

Posted by Larry Hoover on June 29, 2003, at 9:25:11

In reply to Re: Selenium » Larry Hoover, posted by blueheeler on June 23, 2003, at 23:03:58

> >
> > Make sure you add selenium, to a total of at least 200 mcg/day (it should be in the multi, too). Zinc is probably at about 15 mg in the multi, but you should aim for more like 40-50 mg a day.
>
>
> Hi Larry
>
> Here in Australia vitamin manufacturers are required by law to add the following statement on the label of any supplement containing selenium
>
> "This product contains selenium, which is toxic in high doses. Signs of toxicity may include loss of hair and nails. Do not exceed a daily dose of 100 micrograms of selenium from all sources other than food."
>
> What do you know about the Australian recommended doses of selenium in supplement form (of 100mcg MAXIMUM per day) and this warning on the labels of products containing selenium in Australia and the discrepancy between this and the recommended doses of selenium in North America?
>
> Regards
> blueheeler
>
> ***( formerly bluedog but I forgot my password and had to re-register under a new name)***

Hey, dog. How ya been?

It might depend on how much is already in the diet. I know that New Zealanders are chronically deficient in selenium, but I don't know about Aussies. It really depends on the soil.

Here's a quotation from an article in the Jornal of Nutrition, "Selenomethionine: A Review of Its Nutritional Significance, Metabolism and Toxicity", by Gerhard N. Schrauzer


"Dietary Se intakes depend on regional Se availability and the types of foods consumed. In American adults, Se intakes typically range from 80 to 165 µg/d (53) . Although observations of subjects residing in high Se regions or taking Se supplements previously identified Se intakes of up to 724 µg/d by adults as safe, it is considered approximate. To provide a sufficiently wide margin of safety, the reference dose (RfD) for Se from all nutritional sources for a 70-kg human has been set at 350 µg/d (10) , corresponding to 5 µg Se/(kg body · d) or 5 times the recommended dietary allowance. The RfD thus defines as safe the total intake of Se by an American adult who is subsisting on a normal diet and is taking an additional 200 µg Se/d in the form of a nutritional supplement. The RfD may still be revised pending the outcome of ongoing studies by the Environmental Protection Agency, but is unlikely to change significantly in the light of currently available evidence."

The full-text is available at:
http://www.nutrition.org/cgi/content/full/130/7/1653

Lar

 

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poster:Larry Hoover thread:234747
URL: http://www.dr-bob.org/babble/20030624/msgs/237870.html