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Re: Nicotine and brain chemicals

Posted by Paulie on June 9, 2003, at 18:50:12

In reply to Nicotine and brain chemicals, posted by tina on June 9, 2003, at 18:22:40

Nicotine appears to be an MAO-B inhibitor increasing DPA. This is the reasoning why Zyban,which blocks the re-uptake of DPA, can reduce the craving for nicotine.

From http://biopsychiatry.com

SELEGILINE (l-deprenyl)
A recent New York study showed that smokers had on average 40% less of the enzyme, monoamine oxidase type-B, in their brains than non-smokers. Levels returned to normal on their giving up smoking. Not merely is the extra dopamine in the synapses rewarding. The level of MAO-b inhibition smokers enjoy apparently contributes to their reduced incidence of Parkinson's and Alzheimer's disease.

It is much better though to take a DPA agonist than to smoke.

Paul


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poster:Paulie thread:232715
URL: http://www.dr-bob.org/babble/20030609/msgs/232724.html