Posted by Rocket Jackson on April 27, 2003, at 0:55:07
In reply to Is Buspar no better than water?, posted by jflange on April 26, 2003, at 22:22:14
> Rocket and Donna:
> Interesting thread!
> In my experience with Buspar on its own, it was quite good at managing anticipatory anxiety but, oh my, is it ever useless for panicky sensations! I also found Buspar on its own to be more likely to produce s/e's like sleepiness/wooziness, even a downer effect. So I understand how it got such a bad reputation!
> It is a completely different story when Buspar is put into a combination with an SSRI. Buspar absolutely takes the edge off of SSRIs and yet allows one to enjoy the motivating effects of serotonin w/o all the mania/ and low-grade anxiousness that sometimes comes with that. Also, I recently read an article claiming that Buspar enhances the dopamine effect of some SSRIs like Zoloft...
>
> But I wonder how Buspar would behave with Provigil, or indeed with other non-SSRIs, i.e. a benzo ?
> jflangeJflange,
Your thoughts on Buspar are definitely intriguing. Indeed a combination of Buspar/Provigil would be a very interesting trial for SP or anxiety in general. It makes sense how the Buspar/SSRI combo would be helpful, and I'm glad it's working out for you. Do you recall where you found the article on Buspar potentiating the dopaminergic effects of Zoloft? I'd love to get my hands on that. One thing I'm definitely worried about are the possible anti-dopamine effects of the SSRIs (even though Zoloft appears to be a different story, especially in higher doses). I've thought about adding WB again down the road if I run into some sort dopamine depletion apathy or something to that effect.
This is definitely a thought provoking thread. It's great to bounce ideas off of others who are suffering from the same conditions. We'll find that magic bullet (or bullets) eventually!
Thanks,
Rocket
poster:Rocket Jackson
thread:221893
URL: http://www.dr-bob.org/babble/20030423/msgs/222697.html