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Re: SP Zoloft dose

Posted by Rocket Jackson on April 26, 2003, at 0:55:28

In reply to Re: SP Zoloft dose, posted by jflange on April 25, 2003, at 17:52:18

> Hi Rocket:
>
> I take 75mgs/Zoloft a day with 15 mgs of Buspar. I now have nearly 100% reduction in symptoms at these doses for about 9 months.
>
> 75 mgs of Z feels more or less like 50mgs to me, but I have been too lazy to go back down. 100mgs is the level at which one is supposed to get an extra dopamine effect but it made me feel a bit more manic than I am comfortable with.
>
> As for s/e's: no sexual dysfunction after the first month or so. Weight gain: initially yes, but later went away when I cut out sugar, and now I am at the same weight as when I started. Sleep disturbance is a problem at first but is a side effect that usually goes away. The one problem I encountered with Z was muscle stiffness (shoulders/neck/arms) but this seemed to get better once I took a vitamin supplement with Cal/Mag/Potassium on a Psycho-Babble tip.
>
> As for poop-out: it has not happened to me. If a poop-out does happen, Zoloft can be augmented with other things or the dose can be raised. Also, with Klonopin, Zoloft will interact differently (perhaps more efficently - stronger at lower doses? I am not sure, but it is likely). I wouldn't worry to much about that.
>
> Good luck!
> jflange

Wow, thanks for the great info. From your experience and others', it does appear that Zoloft offers its best SP alleviation in the 75-100mg range, most likely from the dopaminergic effect as you mentioned. I'm keeping my fingers crossed that the Z will be as effective as my current Klonopin/Provigil combo. If not, at least I know I have something that works.

Thanks again for the info. I wish you continued success with your current med regimen!

Rocket


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poster:Rocket Jackson thread:221893
URL: http://www.dr-bob.org/babble/20030423/msgs/222503.html