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Re: nortriptyline - under therapeutic level

Posted by SLS on March 20, 2003, at 15:43:50

In reply to Re: nortriptyline - under therapeutic level SLS, posted by johnj on March 20, 2003, at 14:43:34

> I have tried nort at 70 for a week in the past, or 75 mg, but the side effects were killing me. The last time I went to 70 for 2 or 3 days, but felt worse by the 3rd night. I really felt terrible really depressed. I tried to lower my dose and felt bad too. I just don't know if it is the depression returning or withdrawl. Did you have trouble quitting nort? How did you do it and what do you take now. Have you take any AD that has helped? thanks

Hi John.

It is not rare that someone has trouble finding a therapeutic dosage of nortriptyline, yet be partially or transiently responsive to it. There is a tendency for people to respond well to either nortriptyline or desipramine, but not both. This is not a rule, of course. If you have had no luck with everything else, and have been somewhat responsive to nortriptyline, you might consider desipramine.

Right now, I am taking desipramine 300mg, Lexapro 10mg, and Lamictal 150mg. I have seen only minimal results, but I only started Lexapro a few days ago.

I once responded well to a combination of Parnate + desipramine.

- Scott




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