Posted by Ritch on February 27, 2003, at 1:06:15
In reply to Anyone on typical antipsychotics?, posted by JohnV on February 26, 2003, at 13:01:21
> I was wondering if anyone has been on a typical (older gen) antipsychotic for long-term, and would appreciate any information or experiences. Thanks. John V.
FWIW, My first AP was Thorazine (25mg afternoons) back in 1981 for hostility. It worked rather well for that and I didn't get any EPS for the year or so that I was taking it. My pdoc that wrote for it did tell me that increasing it to 50mg would probably cause akathisia (the Thorazine "shuffles"), but I never increased it any (never felt the need to). He said it was bad for plugging up the bile ducts in your liver, but I was never on it long enough to find that out or experience that problem. Stelazine and Haldol *did* cause MAJOR EPS problems right from the getgo and I couldn't take those at all. I wound up on thioridazine 10-30mg/day (Mellaril) with lithium and I didn't get any EPS from that at that dosage. Also, didn't get any depressogenic effects from Mellaril like I did with Thorazine. HOWEVER, I did develop a cataract in one eye during the time I was using it and one of my retinas is pigmented (from that time-which it can cause-cataracts and retinal pigmentation). Of the atypicals, Risperdal caused significant EPS, but it was more cogwheel rigidity/gait disturbances and dystonic reactions in my throat. Seroquel was much more tolerable, but also way too sedative. I don't want to try any of the damn things ever again..period.
poster:Ritch
thread:204030
URL: http://www.dr-bob.org/babble/20030224/msgs/204231.html