Posted by Darwin on February 6, 2003, at 12:28:15
In reply to Re: Been there done that, posted by Larry Hoover on February 6, 2003, at 7:44:08
> Well, apparently the Acceptable Daily Intake of chromium is 25 grams, so taking 600 mg (as they did in this study) is really no big deal.
Larry, I think you got your mg & mcg mixed up and went astray in your calculations.
A daily dose of 25 grams would probably be lethal and 600 mcg (not mg) was used in the study.
The Daily Value of chromium is 120 mcg and chromium supplements usually provide 200 mcg per capsule (167% DV). So, in order to ingest 25 grams of chromium, one would have to take 125,000 capsules per day!
However, I agree with your conclusion that the amount used in the study, 600 mcg per day, is probably safe.
> Altern Med Rev 2002 Jun;7(3):218-35
> The safety and efficacy of high-dose chromium.
> Lamson DS, Plaza SM.
> Bastyr University, Kenmore, WA, USA. firstname.lastname@example.org
> The data on the standards for chromium requirements and the safety of various chromium compounds and doses are reviewed. The 350-fold difference between the acceptable daily intake and the calculated reference dose for humans of 70 mg per day seems without precedent with respect to other nutritional minerals.
I think you should have calculated 70mg/350 rather than 70mg*350. 70mg/350 = 200mcg. So that gives a range of 200mcg to 70mg.