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Re: are atypical ap's all that different?

Posted by JohnL on January 12, 2003, at 8:33:17

In reply to are atypical ap's all that different?, posted by jonh kimble on January 11, 2003, at 20:53:41

> I tried amisulpride at 50mgs/day for social anxiety and dysthymia... but it didnt do anything. does this mean other aps wont? thanks

All the APs work differently. Some work more on serotonin, less on dopamine, and some are just the opposite. Not to mention the varying effects at norepinephrine and histimine receptors.

Amisulpride is strictly just a dopamine med. So if it didn't help you, then an AP with a serotonin and/or norepinephrine component would likely be a better choice for you. Meds like Zyprexa, Risperdal, and Geodon have multiple actions, and that may be just what you need.

Of them all, I favor Zyprexa. But honestly, in a perfect world, you could try each one for about two weeks. After trying each one for two weeks, whichever one you liked the best could be used for a longer term trial. This strategy can save you months and months of trial and error. If an AP is going to work, it is going to be obvious within two weeks. Sure, it takes longer for the full effects to kick in, but good early results are usually a good indicator that you are on target.


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