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Re: Reward Deficiency Syndrome

Posted by Jaynee on December 14, 2002, at 22:28:49

In reply to Reward Deficiency Syndrome, posted by Whit on December 14, 2002, at 22:03:09

I just read an article that mentions this. I had never heard of it before. The article is not really about it, it is about ADHD and obesity.

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=130024

If you don't feel like reading the entire article, this was basically the part of the article that mentions Reward Deficiency Syndrome.

DRD2 and a range of dopamine and other genes have been associated with a "reward deficiency
syndrome" [34] in which insufficient dopamine-mediated "natural" reward leads to use of "unnatural"
rewards, such as substances, gambling, risk taking and inappropriate eating. This syndrome is
associated with obesity [34], and common in ADHD [22]. The DRD4 gene has been associated
with "novelty seeking" traits, said to be greater in substance abusers [30], and individuals with both
DRD2 and DRD4 genetic variations may be especially prone to multiple difficulties (e.g., having both
ADHD and "reward deficiency syndrome") [30], further suggesting obesity and ADHD could share
neurobiological attributes.


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poster:Jaynee thread:131868
URL: http://www.dr-bob.org/babble/20021210/msgs/131869.html