Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Drunk on Zoloft? Simon Sobo MD

Posted by BrittPark on December 12, 2002, at 15:23:53

In reply to Re: Drunk on Zoloft?, posted by Simon Sobo MD on December 12, 2002, at 6:44:03

I enjoyed reading your article, but must say that I don't entirely agree with you. First there are few psychiatrists who believe that simple chemical imbalances like too much or too little of specific neurotransmitters explain mental illnesses. They know that nobody knows how ADs work. Good psychiatrists work phenomenologically, using their experience and data from colleagues and the scientific literature. I don't see anything wrong with this approach. In fact I don't think there is any other rational approach.

Scientifically I don't think you'd find any researcher who believes he/she understands the mechanisms of mental illness and its treatment.
There is in fact much promissing research. In particular tomagraphic imaging of the brain, though in its infancy, has usually found that there are significant chemical and anatomical differences between "normal" and "mentally ill" people. In the future we can hope that such imaging will be used clinically as a diagnostic tool.

Finally psychodynamic and cognitive behavioral approaches to therapy can be very useful. However for people who are severely ill (let's say depressed to the point of suicidality) talk therapy isn't possible until some kind of pharmacological intervention works well enough for the patient to work with a talk therapist.

If I were a psychiatrist (I'm a biologist by training) I would use as my model: medication first and talk therapy as soon as the patient can reason clearly enough. If the patient is cogent enough (perhaps mild depression following loss) drugs might be unnecessary.

Let me just say that the drug companies are doing a terrible job of finding new and better treatments for mental illness. Since the discovery of antidepressants in the 50s there has not been a single new antidepressant shown to be more effective than any other. The opioid system and the dopamine system, to a lesser degree, are ignored in drug research even though they may well be excellent targets for ADs. I could go on but I've babbled too much already.


Britt (Piled higher and Deeper)

P.S. Please continue to post. It's very helpful to have bona fide physicians post to this board.




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:BrittPark thread:123623