Posted by viridis on November 27, 2002, at 1:02:32
In reply to klono dose Re: Clarification re: Gabatril » viridis, posted by Franz on November 25, 2002, at 10:06:18
Klonopin is supposed to have a very long half-life (the time it takes for half of the drug to be fully metabolized), which is why once-a-day dosing is effective for many people. I found that if I took it before bed, though, its effects wore off by the middle of the next day. Taking divided doses seemed alright for the first while and minimized side effects, but once these disappeared (pretty quickly) it just seemed more effective and convenient to take it all at once in the morning. My pdoc was quite comfortable with whatever dosing schedule worked best -- he commented that doctors on the east coast (of the US) prefer once-a-day dosing and those in the west prefer several smaller doses throughout the day.
It sounds like you're especially sensitive to Klonopin. It should be possible to compound it if cutting up the pills into such tiny pieces is too difficult. This means powdering or dissolving it in something so that you can get the dose you want more easily (for example, if you dissolved a pill in a glass of orange juice, you could drink 1/8 glass at intervals to get the dose you want). For many medications this is possible, but I'd ask an expert for advice. You might ask your pharmacist -- a few pharmacies specialize in this approach, and even if yours doesn't, a good pharmacist could probably give you some tips on how to do this most effectively.
I suspect that the side effects will wear off, but everyone is different in their sensitivity to various medications. I hope that it's helping, despite the side effects.