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Re: New Dopamine Drug approved by FDA

Posted by Larry Hoover on November 18, 2002, at 12:15:58

In reply to New Dopamine Drug approved by FDA, posted by Michael D on November 18, 2002, at 12:07:21


> Aripiprazole is believed to exhibit potent partial agonism of D2 dopamine receptors, and is also associated with partial agonism of 5HT1A serotonin receptors and antagonism of 5HT2A serotonin receptors. This medication's goal is to reduce hyperactive dopamine neurons that mediate psychosis and at the same time enhance underactive dopamine neurons that mediate negative and cognitive symptoms (mesocortical pathway).

Interesting. I just posted abstracts showing that DHA (from fish oil) does the same thing for dopaminergic neurotransmission.

 

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poster:Larry Hoover thread:128125
URL: http://www.dr-bob.org/babble/20021116/msgs/128126.html