Posted by LostboyinNC2 on October 3, 2002, at 15:37:30
In reply to Re: Why ADs don’t work on Sad Puppy Dog and others..., posted by AlphaOne on October 1, 2002, at 0:06:04
I found this article which states the exact same thing Ive been saying all along. That the people who need a QUALITY antidepressant the most are the ones least included in antidepressant drug clinical trials. That is, those with severe forms of depression (biological depressions, endogenous depressions, etc.) The people recruited into these new antidepressant drug trials the most are those with dysthymia and moderate depression. Thus, this is the main reason we keep hearing about this "placebo effect" crap. Im so sick and tired of hearing about the placebo effect. I suppose all those SSRI drug side effects like weight gain, delayed orgasm, dry mouth, etc. are "placebo effect" also, huh?
To quote directly from this article, "
"The greater relative benefit of antidepressant therapy among more severely depressed patients (e.g., Elkin et al., 2002, or Thase et al., 1997a) is offhandedly rejected as an artifact or "regression to the mean." Most recently, Khan and colleagues (2002) reported a steady linear relationship between pretreatment severity and the probability of observing a significant drug-placebo difference. The well-replicated observation that milder depressions are more placebo-responsive is not mentioned. Nor is the futility of placebo treatment of psychotic depression."
Psychologists shouldnt even be allowed to write articles on antidepressant placebo effects. Most psychologists are all biased individuals who would rather have the most severe depressive in therapy rather than go on meds.
Anyway here is the article:
http://www.mhsource.com/pt/p020909.html
Eric LOSTBOYinNC
poster:LostboyinNC2
thread:121482
URL: http://www.dr-bob.org/babble/20020930/msgs/122155.html