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switch from venlafaxine to mirtazapine in Bipolar

Posted by swingsnroundabouts on July 29, 2002, at 8:25:16

Hi all

Advice needed. I can't find any literature giving advice on switching from venlafaxine to mirtazapine. As I have Bipolar 1 disorder I am concerned about the change over triggering a manic episode. My doctor discontinued 75mg bds of venlafazine (no taper off) and started 30mg mirtazapine the next day. The reason for the change was ongoing sleep problems on venlafaxine. My sleep is great - trouble is I appear to be suffering from what I think is venlafaxine withdrawal syndrome (dizziness / exhaustion / vertigo) and I'm not sure whether the venlafazine should have been stopped so abruptly. Should the mirtazapine prevent or help with any potential trigger of mania due to the efexor withdrawal? Does anyone know if any literature exists on this as I don't think it does.




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