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Re: Best New Drugs for Depression/Anxiety » JonW

Posted by JohnX2 on June 21, 2002, at 1:27:46

In reply to Re: Best New Drugs for Depression/Anxiety » JohnX2, posted by JonW on June 17, 2002, at 14:39:49

> > Yeah but moclobemide is off patent in the US. No way Roche will
> > fund a clinical trial for a medicine that is immediately a generic.
> > It's too bad. I think they punted the introduction in the US way way
> > back because of the stigma surrounding MAOI hypertensive crisis (the pdocs
> > would never understand the reversable MAOI concept, duh).
> > You'd think they could make a minor inert tweak to the chemical structure to
> > get Patent status.
> >
> > John
>
> But like you said, even if they could do it, there's all the stigma surrounding the MAOIs. If it weren't about money moclobemide may never have been developed, but if it weren't about money, moclobemide would be in the US right now. I think it's a catch 22 of sorts. Does this mean that other countries are able to understand the concept of *reversible* and we aren't? I hope not, because that's embarassing. I was at a lecture at Princeton University a year or so ago about evolution and they said that of all the nations in the world we have the lowest percentage of people who accept the theory of evolution. I'm speechless on that one, these things just baffle me!
>
> Jon

Some good points. I think that the cost of getting the medication
through the regulatory commissions in the foreign countries is much
cheaper thus justifying the risk/reward of the investment by Roche.
Ultimately good marketing would get around the hypertensive crisis
issue.

Are you a Princeton Alum/Attendee?

John


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URL: http://www.dr-bob.org/babble/20020617/msgs/110386.html