Posted by Ritch on May 13, 2002, at 9:50:37
In reply to Re: No resp.=Depress-severe/Need help w/ old ADs!, posted by Lia Mason on May 12, 2002, at 23:18:01
>........ I'm of the fatiguing depression type, too. The MAO's were great, but I couldn't take the side effects. I'm on a combo of sam-e and imipramine now. Re: orthostatic hypo... I had it bad on Nortriptyline and Nardil and it's very minor on imipramine. I hardly notice it. Imipramine is also a lot less sedating than Nortriptyline for me. The drag with these drugs (tricyclics) is that you can bypass side effects by going up very slowly, but that means you take A LONG time to reach a therapeutic dose.
> If you can tolerate Wellbutrin it's worth a shot. It made me jittery, but most reports I've heard are quite positive.
> Hang in. Good Luck.
Hope you don't mind my asking a question, but how much imipramine are you taking? I am curious, because it is a possibility for me and I had taken nortriptyline before and wonder if imipramine might work better. You said you had *less* orthostatic hypotension on imipramine-nortrip. usually causes less not the other way around (which makes imipramine more interesting to me). Wellbutrin and desipramine made me too nervous, and pstims work but they are too much of a headache with the CII crap.