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Zoloft Vs Clomapramine Mech of Action

Posted by tinker on May 6, 2002, at 7:42:24

In reply to Re: ZOLOFT and norepinephrine, posted by JohnX2 on April 17, 2002, at 0:14:48

I am trying to understand the difference in action between zoloft and clomipramine. I have noticed that there appears to be a significant difference in the blockade levels of 5HT1, 5HT2, Acetylchonine, Histamine, D2. Can anyone comment on exactly what this means, and how significant is it. I am trying to understand why I developed tinnitus from zoloft, I was able to take clomipramine for years without that when the levels of seratonin reuptake are basically the same. Thanks to all.


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