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Re: Help - yet another thread on Lamictal dosing. Cindylou

Posted by Emme on May 1, 2002, at 8:34:17

In reply to Re: Help - yet another thread on Lamictal dosing. Emme, posted by Cindylou on April 30, 2002, at 21:41:41

Hi Cindy,

Thanks for your thoughtful post. So, maybe the higher dose is going to be too high for me. I just hit 100 today and I am going to see how it goes for a couple of weeks, see if I feel better or worse, and then consult with my doctor with the new "data". Maybe I'll have to drop it again. 62.5 mg seemed to be the magic number when positive things started to happen. It seemed like 75 was a good dose, at least for a while. 50 or below didn't have antidepressant activity for me.

For a while I was trying Celexa in addition to Lamaictal and neurontin and klonopin and I felt worse on only 2 mg. I was freezing cold all the time, , exhausted, felt cruddy, and at one point my moods were up and down on a daily basis for five days straight before I gave it up. I guess we haven't ruled out a dash of an antidepressant, but we'd have to think carefully about which one.

Yeah, I like Neurontin. For a med-sensitive person, I find it easy to take and a nice augmenter for anxiety. I hope it helps you.

That's too bad you had to ditch the lamictal. I can sympthize about giving up the meds and having things go haywire. I've tried that also, tjust to temporarily wipe the slate clean after trying a lot of meds. After a couple of weeks of complete washout... wasn't pretty.

I'm sorry you have the pregnancy concerns. I think about it also, though it's further off for me. Have you consulted with a reproductive psychiatrist, or a prenatal pharmacologist. (Yes, people do specialize in such areas.) I have a friend on a very complicated pain-control regime with some potentially nasty stuff. When she was gearing up to conceive, she consulted with a specialist in how drugs affect the fetus and got some very surprising (and encouraging) answers about which drugs were okay and which ones weren't. So...although no meds would be the most desirable, go straight to the top and get the most up to date info before making any decisions for or against pregnancy on meds. It'd be great for you to be able to get going on the pregnancy you want.

I wish the best to you also. I've learned from your posts. We seem to have similar sensitivies to drugs. I can't recall - what's your dx? My doctor thinks I am in the bipolar spectrum. Of course I guess the treatment matters more than the label.


> Hi Emme,
> So sorry to hear you're having trouble! The same thing happened to me over the holidays. I was taking 75 mg of Lamictal and doing okay, but when I tried increasing it to 100, and then 125, I felt more and more miserable. Depressed, tired, and so bloated I had to go out and buy new pants! I do believe it was the increased Lamictal dose that caused those reactions -- when I went back down to 75 mg I felt better.
> My pdoc attended a conference recently where they presented research that people can be helped on as low as 50 mg of Lamictal. Perhaps you'd feel better on even a lower dose than 75? Are you on any other med? Maybe you could augment the Lamcital with an AD to help with your moods?
> As for me, I have recently stopped Lamictal, since it wasn't helping enough, only a small amount, and because I wasn't able to increase the dose, AND I couldn't add on an AD without horrible side effects. Also, I wanted to try to get pregnant, so I thought I'd give it a go with no meds.
> After stopping Lamictal, things really got out of control, as far as depression and agitation -- so I could tell that the Lamictal did help me some!
> Now I am trying Neurontin (you mentioned this to me as an option, I believe). I just started yesterday, but so far, so good. I guess the pregnancy will have to wait (or I'll have to take the risk of being pregnant while on meds.)
> I wish the best to you! You have been a great help to me over the past months.
> Take care, and keep me posted ...
> cindy
> > Hi Folks,
> >
> > I had a lot of improvement with 75 mg Lamictal and was tolerating it well. Then I got really stressed out over some stressful things and lost some mood control. So...I'm increasing Lamictal and am at 95 now - up to 100 this week. At the moment I'm miserable. I feel very tired and spacey and I feel depressed. I can't figure out if it's just adjustment to the increase (I've had some difficulties during increases before) and maybe I'm feeling depressed because I'm so tired. Or maybe I just can't tolerate this dose and should back it down to 75 again - I tend to be sensitive and use low doses of stuff. Or if it's even just not high enough? I don't know how to dose this stuff, though I suppose I should hang out at 100 mg for a couple of weeks if I can and see how it shakes out....
> >
> > Anyway...I remember there being discussions about raising/lowering lamictal and optimal dosages. I was curious about where people are at with this drug (Cindylou? Hattree?). Has anyone felt worse when they went up on Lamictal and felt better moodwise (as well as physically) when they went back down a bit?
> >
> > Thanks so much.
> > Emme




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