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Re: Depakote/Topamax/Wellbutrin..something seems wrong » pand0ra

Posted by Ritch on April 29, 2002, at 12:48:31

In reply to Depakote/Topamax/Wellbutrin..something seems wrong, posted by pand0ra on April 29, 2002, at 2:20:55

> I was recently prescribed 500mg of Depakote,150mg of Wellbutrin, and 25mg of Topamax with an increase of 25mg per week for four weeks to lessen the side effects. It's been exactly one week since I've been taking these medicines and it's been one hell of a ride. I'm under the assumption I was diagnosed as bi-polar, since she never actually said I was bi-polar, when I feel that I'm not manic, I was just suffering from depression. In this past week I've felt all my love for other people turn to hate, I'm engaged and I've started to hate my fiance for no reason, I've felt I've lost my sense of humor which was my only strong point, I feel that I have been stable but I haven't been generally happy. I've also noticed that I have a hard time pronouncing words that were once easy. Today was especially rough which is why I decided to write. I paced around the house, looking for things to clean to keep my mind occupied because I felt suicidal or like I wanted to harm myself. I don't want to be taken off the Topamax because of the weight loss effects and I'm not sure of the Wellbutrin, it's the Depakote that makes me wonder, because it's the anti-mania drug out of the three (correct me if I'm wrong). I went to a psychologist before the psychiatrist who told me that it sounded like I was depressed, and that I got that way because when a person is sad for a long period of time their brain slows down on making serotonin. So I was hoping for an SSRI from the psychiatrist. Anyways, if anyone has any comments or suggestions I'd really appreciate it. I know that I don't like the way that I feel, and I'm wondering if it'll all go away eventually or if I should get off one of these meds. Please help!


Uh oh! It sounds like Wellbutrin-induced dysphoria to me. It made me very grouchy, hostile, and hateful towards other people at times. My ordinarily warm personality got quite cold and brittle. I had plenty of energy, but it made me mean. The Topamax is probably the med that is causing your word-finding problems, just my 2 cents. Depakote will do that to me as well, but nothing like Topamax! You need to tell your doctor about all of this ASAP. The Depakote+Topamax combination could be causing a toxic reaction (unlikely-but still possible).

Mitch


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poster:Ritch thread:104388
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